What to know about 1000-Lb Sisters season 8, including the latest news, potential premiere date, potential cast, etc, now that the ongoing season is coming to a close. 1000-Lb Sisters follows the lives of siblings Amy and Tammy Slaton as they navigate significant weight-loss journeys. The show delves into their personal challenges, family dynamics, and the emotional and physical hurdles they face in pursuit of healthier lives. Since 2020, the series has garnered attention for its raw portrayal of the sisters’ struggles and triumphs. The 1000-Lb Sisters season 7 continued to explore the transformations of Tammy and Amy.